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GO_term: GO:0000703   

GO:0000703DefinitionCatalysis of the formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. Enzymes with this activity recognize and remove oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
Termpyrimidine-specific oxidized base lesion DNA N-glycosylase activity
TypeMolecular_function
Parent Instance_of (3)
Attributes_of Index Ancestor (39)
Descendent (76)