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GO_term: GO:0000703   

GO:0000703DefinitionCatalysis of the formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. Enzymes with this activity recognize and remove oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
Termpyrimidine-specific oxidized base lesion DNA N-glycosylase activity
TypeMolecular_function
Parent Instance_of (3)
Attributes_of Index Ancestor (39)
Descendent GO:0000251
GO:0000252
GO:0000253
GO:0000254
GO:0000703
GO:0019004
GO:0009381
GO:0003908
GO:0046403
GO:0046404
GO:0004536
GO:0004537
GO:0004520
GO:0000704
GO:0004844
GO:0009456
GO:0016846
GO:0016847
GO:0047654
GO:0004121
GO:0008799
GO:0016225
GO:0004123
GO:0019148
GO:0047803
GO:0008826
GO:0047804
GO:0047869
GO:0004408
GO:0047982
GO:0050017
GO:0004462
GO:0018826
GO:0050271
GO:0009000
GO:0050312
GO:0009985
GO:0016850
GO:0018836
GO:0018835
GO:0016852
GO:0004325
GO:0016851
GO:0016849
GO:0008685
GO:0004016
GO:0008294
GO:0047805
GO:0047396
GO:0004383
GO:0042408
GO:0004436
GO:0008265
GO:0030366
GO:0009392
GO:0019007
GO:0016217
GO:0008755
GO:0016491
GO:0030342
GO:0019168
GO:0008682
GO:0004033
GO:0003826
GO:0030611
GO:0008794
GO:0030612
GO:0042411
GO:0030065
GO:0045441
GO:0001512
GO:0004154
GO:0015036
GO:0015037
GO:0015038
GO:0016836