GO_term: GO:0043223   

GO:0043223	Definition	A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome.The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
	Term	cytoplasmic SCF ubiquitin ligase complex
	Type	Cellular_component
	Parent	Instance_of (2)
	Attributes_of	Index	Ancestor (22)
			Descendent	GO:0043223

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