RNAiDB Tree View

GO_term: GO:0045107

GO:0045107	Definition	Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.
	Term	intermediate filament polymerization
	Type	Biological_process
	Child	Component	GO:0030839
	Parent	Instance_of	GO:0045105
			GO:0051258
	Attributes_of	Index	Ancestor	GO:0000368
				GO:0001921
				GO:0003673
				GO:0006996
				GO:0007010
				GO:0007028
				GO:0007092
				GO:0007582
				GO:0008150
				GO:0008151
				GO:0008152
				GO:0009987
				GO:0016043
				GO:0018228
				GO:0019538
				GO:0030579
				GO:0030833
				GO:0030838
				GO:0030842
				GO:0030844
				GO:0042529
				GO:0042989
				GO:0043170
				GO:0043328
				GO:0044237
				GO:0044238
				GO:0044260
				GO:0044267
				GO:0045103
				GO:0045105
				GO:0045874
				GO:0045107
				GO:0045856
				GO:0050875
				GO:0051570
				GO:0051574
				GO:0051258
			Descendent	GO:0030839
				GO:0030840
				GO:0030841
				GO:0045107