GO_term: GO:0045250   

GO:0045250	Definition	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in bacteria; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.
		Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
	Term	pyruvate dehydrogenase complex (sensu Bacteria)
	Type	Cellular_component
	Parent	Instance_of	GO:0045254
		Component_of	GO:0005737
	Attributes_of	Index	Ancestor	GO:0000274
				GO:0000276
				GO:0000500
				GO:0000925
				GO:0000927
				GO:0001741
				GO:0003673
				GO:0005575
				GO:0005622
				GO:0005623
				GO:0005737
				GO:0005824
				GO:0009656
				GO:0010006
				GO:0030085
				GO:0030685
				GO:0030688
				GO:0030692
				GO:0031358
				GO:0031616
				GO:0042648
				GO:0043234
				GO:0045250
				GO:0045254
				GO:0045265
				GO:0046612
			Descendent	GO:0045250

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