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GO_term: GO:0046849   

GO:0046849DefinitionThe continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.
Termbone remodeling
TypeBiological_process
Child Component GO:0001503
GO:0045453
GO:0046850
Parent Instance_of GO:0007582
GO:0050874
Attributes_of MotifINTERPRO:IPR010892
Index Ancestor (27)
Descendent (23)