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Gene: H04J21.3 
| H04J21.3 | SMap | S_parent | Sequence | H04J21 | ||
|---|---|---|---|---|---|---|
| Chromosome | III | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | gip | ||||
| Allele (6) | ||||||
| Contained_in_operon | CEOP3075 | |||||
| Structured_description | Provisional_description | gip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization. | Paper_evidence | WBPaper00005041 | ||
| WBPaper00005320 | ||||||
| Person_evidence | WBPerson1843 | |||||
| Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| Concise_description | gip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization. | |||||
| Molecular_info (6) | ||||||
| Experimental_info | RNAi_result | Cenix:140-a1 | ||||
| Cenix:338-a3 | ||||||
| Cenix:341-b7 | ||||||
| JA:H04J21.3 | ||||||
| TH:338a3 | ||||||
| TH:341b7 | ||||||
| WB_RNAi_result (9) | ||||||
| Y2H_bait (49) | ||||||
| Reference | WBPaper00005320 | |||||
| WBPaper00005041 | ||||||
| Remark | Sequence connection from [Hannak E], 02/06/11 krb. | |||||
| Method | Gene |
