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Gene: H25P06.2 
| H25P06.2 | SMap | S_parent | Sequence | SUPERLINK_CB_IR | ||
|---|---|---|---|---|---|---|
| Chromosome | I | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | cdk | ||||
| Allele (5) | ||||||
| GO_term (5) | ||||||
| Structured_description | Provisional_description | cdk-9 encodes an ortholog of the metazoan transcription elongation factor kinase CDK-9; it is required for general expression of early embryonic genes, and thought (in conjunction with partners such as cyclin T) to form a transcription factor (P-TEFb) that which prevents transcription from stalling in vitro. | Paper_evidence | WBPaper00004192 | ||
| WBPaper00005411 | ||||||
| WBPaper00012800 | ||||||
| Person_evidence | WBPerson567 | |||||
| Curator_confirmed | WBPerson567 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| Heat shock genes are rendered independent of CDK-9 when not only cdk-9, but also spt-4 and spt-5 are inhibited by RNAi, implying that SPT-4/SPT-5 antagonize CDK-9 function in vivo. | ||||||
| CDK-9 is required for phosphorylation of the Ser-2 residue of the RNA Polymerase II C-terminal domain (CTD) repeat, but not for most CTD Ser-5 phosphorylation. | ||||||
| Concise_description | cdk-9 encodes an ortholog of the metazoan transcription elongation factor kinase CDK-9; it is required for general expression of early embryonic genes, and thought (in conjunction with partners such as cyclin T) to form a transcription factor (P-TEFb) that which prevents transcription from stalling in vitro. | |||||
| Molecular_info (6) | ||||||
| Experimental_info | RNAi_result | JA:H25P06.2a | ||||
| Simmer:H25P06.2a:Screen_A | ||||||
| Simmer:H25P06.2a:Screen_B | ||||||
| Cenix:118-b11 | ||||||
| WB_RNAi_result (5) | ||||||
| Interaction | WBInteraction0003603 | |||||
| Reference | WBPaper00004192 | |||||
| WBPaper00005411 | ||||||
| WBPaper00005725 | ||||||
| WBPaper00005845 | ||||||
| WBPaper00017762 | ||||||
| WBPaper00026473 | ||||||
| Method | Gene |
