K05F1.2 | SMap | S_parent | Sequence | K05F1
|
| Chromosome | II |
|
Identity (5)
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Gene_info
| Gene_class | msp
|
| |
Phenotype
| Cluster of two genes four pseudogenes including msp-142 (transcribed). |
| | | [C.elegansII] NMK. Encodes MSP (16kD). Defines cluster of two genes, four pseudogenes including msp-142 (transcribed). [Ward et al. (1988); BA] |
| | GO_term | GO:0005198
| IEA
| Inferred_automatically |
| |
Structured_description
| Provisional_description | msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Paper_evidence (4)
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| | | | | Curator_confirmed | WBPerson324
|
| | | | | Date_last_updated | 31 Mar 2005 00:00:00 |
| | | Concise_description | msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
|
Molecular_info
| Corresponding_CDS | K05F1.2
|
| | Corresponding_protein | WP:CE02806
|
| |
Corresponding_PCR_product
| smd_C34F11.4
|
| | | smd_F36H12.7
|
| | | smd_F36H12.7:2
|
| | | smd_F36H12.8
|
| | | smd_K05F1.2
|
| | | smd_R13H9.4
|
| | | smd_ZK354.11
|
| | | smd_ZK1248.4
|
| | | smd_ZK1248.4:2
|
| | | smd_ZK1251.6
|
| | | sjj_R13H9.4
|
| | | sjj_R05F9.13
|
| | | sjj_ZK1248.17
|
| | | sjj_R05F9.8
|
| | | sjj_ZK1248.6
|
| | | sjj_ZK1251.6
|
| | | sjj_R05F9.5
|
| | | sjj_ZK1248.4
|
| | | sjj_ZK354.11
|
| | | sjj_C09B9.6
|
| | | sjj_C34F11.4
|
| | | sjj_K05F1.7
|
| | | sjj_F58A6.8
|
| | | sjj_F36H12.7
|
| | | sjj_K05F1.2
|
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Corresponding_RNAi_reagent (32)
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Experimental_info
| RNAi_result | Cenix:206-e1
|
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WB_RNAi_result (76)
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| | Expr_pattern | Expr3417
|
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Reference (6)
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| Method | Gene
|