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Gene: K05F1.7   

K05F1.7SMapS_parentSequenceK05F1
ChromosomeII
Identity (5)
Gene_info Gene_classmsp
Phenotype[C.elegansII] NMK. Pseudogene for MSP; msp-142 cluster. [Ward et al. (1988); BA]
GO_termGO:0005198 IEA Inferred_automatically
Structured_description Provisional_descriptionmsp-63 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. Paper_evidence WBPaper00001023
WBPaper00002143
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated31 Mar 2005 00:00:00
Concise_descriptionmsp-63 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Molecular_info Corresponding_CDSK05F1.7
Corresponding_proteinWP:CE02811
Corresponding_PCR_product (8)
Corresponding_RNAi_reagent Cenix:211-b4
sjj_K05F1.7
mv_K05F1.7
mv_ZK1248.6
yk307d11
Cenix:13-c7
Cenix:206-e1
Cenix:236-b4
sjj_ZK1248.17
mv_ZK1248.17
sjj_ZK1248.6
mv_K05F1.2
Experimental_info RNAi_result Cenix:211-b4
JA:K05F1.7
WB_RNAi_result (65)
Expr_patternExpr3417
ReferenceWBPaper00024312
MethodGene