RNAiDB Tree View

Gene: K07F5.2

K07F5.2	SMap	S_parent	Sequence	K07F5
	Chromosome	IV
	Identity (5)
	Gene_info	Gene_class	msp
		Phenotype	[C.elegansII] NMK. Encodes MSP (16kD); msp-56 cluster. [Ward et al. (1988); BA]
		GO_term	GO:0005198	IEA	Inferred_automatically
		Structured_description	Provisional_description	msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.	Paper_evidence	WBPaper00001023
						WBPaper00002143
						WBPaper00004591
						WBPaper00005670
					Curator_confirmed	WBPerson324
					Date_last_updated	31 Mar 2005 00:00:00
			Concise_description	msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
	Molecular_info	Corresponding_CDS	K07F5.2
		Corresponding_protein	WP:CE03853
		Corresponding_PCR_product (45)
		Corresponding_RNAi_reagent (52)
	Experimental_info	RNAi_result	Cenix:14-g4
			JA:K07F5.2
		WB_RNAi_result (69)
		Expr_pattern	Expr3417
	Reference	WBPaper00001023
		WBPaper00001024
		WBPaper00021018
		WBPaper00024312
	Method	Gene