K08F4.10 | SMap | S_parent | Sequence | K08F4
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| Chromosome | IV |
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Identity (5)
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Gene_info
| Gene_class | msp
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Structured_description
| Provisional_description | msp-37 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Paper_evidence
| WBPaper00001023
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| | | | | | WBPaper00002143
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| | | | | | WBPaper00004591
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| | | | | | WBPaper00005670
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| | | | | Curator_confirmed | WBPerson324
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| | | | | Date_last_updated | 31 Mar 2005 00:00:00 |
| | | Concise_description | msp-37 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
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Molecular_info
| Corresponding_pseudogene | K08F4.10
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Corresponding_PCR_product (7)
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Corresponding_RNAi_reagent (9)
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Experimental_info
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WB_RNAi_result (8)
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| | Expr_pattern | Expr3417
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| Reference | WBPaper00015440
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| Method | Gene
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