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Gene: K11G12.7   

K11G12.7SMapS_parentSequenceK11G12
ChromosomeX
Identity (5)
Gene_info Gene_classacr
GO_term (9)
Contained_in_operonCEOPX158
Structured_description Provisional_descriptionacr-3 encodes a non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; ACR-3 functions as a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-38, an nAChR alpha subunit, the resulting hetero-oligomer can form levamisole-gated channels; ACR-3 is a member of the UNC-29-like group of nAChR subunits. Paper_evidence WBPaper00003080
WBPaper00003425
WBPaper00005427
WBPaper00005594
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionacr-3 encodes a non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; ACR-3 functions as a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-38, an nAChR alpha subunit, the resulting hetero-oligomer can form levamisole-gated channels; ACR-3 is a member of the UNC-29-like group of nAChR subunits.
Molecular_info (5)
Experimental_info RNAi_result Cenix:30-a3
JA:K11G12.7
WB_RNAi_result JA:K11G12.7
Cenix:30-a3
Reference (13)
Remark [Baylis HA] originally identified by Mike Squire and John Fleming as another putative non-alpha nicotinic acetylcholine receptor subunit gene adjacent to acr-2. We believe that the acr-3 protein begins "MQKIWLF...". The predicted protein K11G12.2 is a concatenated version of acr-2 and acr-3.
LINK TO K11G12.2 REMOVED BY AGREEMENT. [sdm 0107]
MethodGene