Gene: R04F11.1   

R04F11.1	SMap	S_parent	Sequence	R04F11
	Chromosome	V
	Identity (5)
	Gene_info	GO_term	GO:0016021	IEA	Inferred_automatically
		Structured_description	Provisional_description	R04F11.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; R04F11.1 is worm-specific, with obvious homologs only in C. elegans; R04F11.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.	Paper_evidence (6)
					Person_evidence	WBPerson567
					Curator_confirmed	WBPerson567
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	R04F11.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; R04F11.1 is worm-specific, with obvious homologs only in C. elegans; R04F11.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
	Molecular_info	Corresponding_CDS	R04F11.1
		Corresponding_protein	WP:CE06232
		Corresponding_PCR_product	sjj_R04F11.1
		Corresponding_RNAi_reagent	Cenix:97-h9
			sjj_R04F11.1
	Experimental_info	RNAi_result	Cenix:97-h9
			JA:R04F11.1
		WB_RNAi_result	JA:R04F11.1
			Cenix:97-h9
	Method	Gene

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