Gene: R10A10.2
R10A10.2 | SMap | S_parent | Sequence | R10A10 | ||
---|---|---|---|---|---|---|
Chromosome | I | |||||
Identity (5) | ||||||
Gene_info | Gene_class | rbx | ||||
GO_term | GO:0004842 | IEA | Inferred_automatically | |||
GO:0008270 | IEA | Inferred_automatically | ||||
GO:0016567 | IEA | Inferred_automatically | ||||
GO:0000151 | IEA | Inferred_automatically | ||||
Structured_description | Provisional_description | The R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34. | Paper_evidence | WBPaper00012757 | ||
Person_evidence | WBPerson567 | |||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
Concise_description | The R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34. | |||||
Molecular_info (5) | ||||||
Experimental_info | RNAi_result | Cenix:16-d5 | ||||
JA:R10A10.2 | ||||||
PF:GL1_7B3 | ||||||
WB_RNAi_result (6) | ||||||
Method | Gene |