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Gene: R10A10.2   

R10A10.2SMapS_parentSequenceR10A10
ChromosomeI
Identity (5)
Gene_info Gene_classrbx
GO_term GO:0004842 IEA Inferred_automatically
GO:0008270 IEA Inferred_automatically
GO:0016567 IEA Inferred_automatically
GO:0000151 IEA Inferred_automatically
Structured_description Provisional_descriptionThe R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34.Paper_evidenceWBPaper00012757
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionThe R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34.
Molecular_info (5)
Experimental_info RNAi_result Cenix:16-d5
JA:R10A10.2
PF:GL1_7B3
WB_RNAi_result (6)
MethodGene