Gene: R13H9.4
R13H9.4 | SMap | S_parent | Sequence | R13H9 | ||
---|---|---|---|---|---|---|
Chromosome | IV | |||||
Identity (5) | ||||||
Gene_info | Gene_class | msp | ||||
Phenotype | [C.elegansII] NMK. Encodes MSP (16kD); msp-113 cluster. [Ward et al. (1988); BA] | |||||
GO_term | GO:0005198 | IEA | Inferred_automatically | |||
Structured_description | Provisional_description | msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence (5) | |||
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 06 May 2005 00:00:00 | |||||
Concise_description | msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | |||||
Molecular_info | Corresponding_CDS | R13H9.4 | ||||
Corresponding_protein | WP:CE02806 | |||||
Corresponding_PCR_product (58) | ||||||
Corresponding_RNAi_reagent | Cenix:242-c6 | |||||
sjj_R13H9.4 | ||||||
sjj_C04G2.4 | ||||||
mv_ZK354.4 | ||||||
sjj_ZK354.11 | ||||||
sjj_R05F9.8 | ||||||
Cenix:14-e7 | ||||||
sjj_C34F11.4 | ||||||
sjj_F32B6.6 | ||||||
Cenix:203-f6 | ||||||
Cenix:13-d1 | ||||||
sjj_R13H9.2 | ||||||
sjj_ZK354.1 | ||||||
sjj_C34F11.6 | ||||||
yk381d1 | ||||||
mv_C34F11.4 | ||||||
sjj_K08F4.8 | ||||||
sjj_F36H12.7 | ||||||
sjj_F58A6.8 | ||||||
sjj_R05F9.3 | ||||||
mv_ZK1248.6 | ||||||
Cenix:16-c9 | ||||||
sjj_ZK546.6 | ||||||
Cenix:242-d2 | ||||||
mv_F36H12.7 | ||||||
mv_C34F11.6 | ||||||
sjj_K07F5.3 | ||||||
sjj_F26G1.7 | ||||||
Cenix:246-b8 | ||||||
sjj_ZK546.3 | ||||||
yk380e3 | ||||||
Cenix:13-c7 | ||||||
sjj_Y59E9_120.c | ||||||
Cenix:206-e1 | ||||||
Cenix:243-c6 | ||||||
Cenix:242-h2 | ||||||
sjj_K07F5.1 | ||||||
mv_C09B9.6 | ||||||
mv_F26G1.7 | ||||||
Cenix:211-g4 | ||||||
sjj_R05F9.13 | ||||||
sjj_T13F2.11 | ||||||
Cenix:247-a1 | ||||||
Cenix:205-e12 | ||||||
Cenix:14-g4 | ||||||
Cenix:245-g4 | ||||||
mv_ZK546.6 | ||||||
sjj_Y4C6A.c | ||||||
sjj_T13F2.10 | ||||||
Cenix:13-f11 | ||||||
sjj_K07F5.2 | ||||||
sjj_F09C12.7 | ||||||
Cenix:13-d7 | ||||||
yk384g8 | ||||||
mv_R05F9.8 | ||||||
sjj_ZK1248.6 | ||||||
mv_Y59H11AM.d | ||||||
sjj_C09B9.6 | ||||||
yk386a12 | ||||||
yk387c2 | ||||||
yk370d1 | ||||||
sjj_ZK354.5 | ||||||
mv_K05F1.2 | ||||||
mv_F32B6.6 | ||||||
Cenix:242-g2 | ||||||
Cenix:242-g7 | ||||||
sjj_ZK354.4 | ||||||
Experimental_info | RNAi_result | Cenix:242-c6 | ||||
JA:R13H9.4 | ||||||
WB_RNAi_result (68) | ||||||
Expr_pattern | Expr3417 | |||||
Reference (3) | ||||||
Method | Gene |