RNAiDB Tree View

Gene: T05A6.1

T05A6.1	SMap	S_parent	Sequence	T05A6
	Chromosome	II
	Identity (5)
	Gene_info	Gene_class	cki
		Allele	gk132	Inferred_automatically	From strain object: VC170
		Strain	VC170
			VT825
		GO_term	GO:0004861	IEA	Inferred_automatically
			GO:0007050	IEA	Inferred_automatically
			GO:0005634	IEA	Inferred_automatically
		Structured_description	Provisional_description	cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.	Paper_evidence	WBPaper00003201
					Person_evidence	WBPerson567
					Curator_confirmed	WBPerson567
					Date_last_updated	17 Jun 2004 00:00:00
				Heterochronic genes regulate cki-1 expression in vulval precursor cells.
			Concise_description	cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.
	Molecular_info (6)
	Experimental_info (5)
	Reference (56)
	Remark	Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene