Gene: T05G5.3
T05G5.3 | Evidence | CGC_data_submission | ||||
---|---|---|---|---|---|---|
SMap | S_parent | Sequence | T05G5 | |||
Chromosome | III | |||||
Identity (5) | ||||||
Gene_info | Gene_class | cdk | ||||
Allele (7) | ||||||
Phenotype | [C.elegansII] NMK. Encodes 38 kD protein, homolog of fission yeast p34 cdc2 kinase, 65% identity to human cdc2 but has sequence PSTAVR rather than PSTAIR; can complement some alleles of budding yeast CDC28. [Mori et al. 1994; PS] | |||||
Strain (5) | ||||||
GO_term (9) | ||||||
Structured_description | Provisional_description | cdk-1 encodes a cyclin-dependent kinase, orthologous to and functionally interchangeable with CDC28 from S. cerevisiae; CDK-1 is required for cell-cycle progression through M phase in both meiosis and mitosis. | Paper_evidence | WBPaper00002097 | ||
WBPaper00003554 | ||||||
WBPaper00004192 | ||||||
Person_evidence | WBPerson567 | |||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
While maternal ncc-1 product is sufficient for embryogenesis, zygotic expression is required for cell divisions during larval development. | ||||||
CDK-1 falls into an orthologous group of cyclin-dependent kinases that includes CDC28 from S. cerevisiae, cdc2 from S. pombe, and CDK1-3 from human beings. | ||||||
Concise_description | cdk-1 encodes a cyclin-dependent kinase, orthologous to and functionally interchangeable with CDC28 from S. cerevisiae; CDK-1 is required for cell-cycle progression through M phase in both meiosis and mitosis. | |||||
Molecular_info (6) | ||||||
Experimental_info | RNAi_result (8) | |||||
WB_RNAi_result | TH:321b3 | |||||
JA:T05G5.3 | ||||||
[cgc5224]:cdk-1 | ||||||
Simmer:T05G5.3 | ||||||
MV_SV:mv_T05G5.3 | ||||||
Cenix:321-b3 | ||||||
Cenix:341-e4 | ||||||
PF:GL1_6A3 | ||||||
Expr_pattern | Expr551 | |||||
Expr1328 | ||||||
Y2H_bait | Y2H011508 | |||||
Reference (36) | ||||||
Remark | Sequence connection from [Golden A] | |||||
old_name ncc-1 becomes new_name cdk-1 from [Golden A]. | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |