T10G3.6 | Evidence | Person_evidence | WBPerson1846
|
| SMap | S_parent | Sequence | T10G3
|
| Chromosome | V |
|
Identity (5)
|
|
Gene_info
| Gene_class | gut
|
| |
Allele
| it92
|
| | | lw6
|
| | | gk407
| Inferred_automatically | From strain object: VC904 |
| | | gk402
| Inferred_automatically | From strain object: VC989 |
| |
Phenotype
| [C.elegansII] lw6 : E cells fail to gastrulate, division rate does not slow; mutant EMS not responsive to WT P2 induction. lw6/Df similar. OA>10: it92, lw63 (Gro, sterile). Cloned: cosmid rescue (T10G8). [EH; CB] |
| | | [Shaw JE] lw6 and it92 are not null alleles. lw6 and it92 are recessive, strict maternal effect lethal. Dead embryos arrest development with approximately normal cell number but no morphogenesis. Dead embryos are highly penetrant for lack of both differentiated gut cells and pharyngeal muscle. Other tissues (hypodermal, neuronal, body-wall muscle) are present. Early defects in E lineage,i.e. early 2E to 4E division and failure to gastrulate, highly penetrant. Null phenotype likely recessive slow-growing, sterile adult. |
| |
Strain
| VC904
|
| | | VC989
|
| |
GO_term
| GO:0006397
| IEA
| Inferred_automatically |
| | | GO:0030529
| IEA
| Inferred_automatically |
| | | GO:0005634
| IEA
| Inferred_automatically |
| | | GO:0005732
| IEA
| Inferred_automatically |
| |
Structured_description
| Provisional_description | gut-2 encodes a member of the Sm protein family with highest similarity to human U6 snRNA-associated Sm-like protein, LSm2, that affects embryonic viability. |
Paper_evidence
| WBPaper00012624
|
| | | | | | WBPaper00023072
|
| | | | | Person_evidence | WBPerson48
|
| | | | | Curator_confirmed | WBPerson48
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Concise_description | gut-2 encodes a member of the Sm protein family with highest similarity to human U6 snRNA-associated Sm-like protein, LSm2, that affects embryonic viability. |
|
Molecular_info (6)
|
|
Experimental_info
|
RNAi_result
| JA:T10G3.6
|
| | | Simmer:T10G3.6:Repeat_a
|
| | | Simmer:T10G3.6:Screen
|
| | | Cenix:104-h10
|
| |
WB_RNAi_result
| JA:T10G3.6
|
| | | Simmer:T10G3.6:Repeat_a
|
| | | Simmer:T10G3.6:Screen
|
| | | Cenix:104-h10
|
|
Reference (6)
|
| Remark | The gut-2 gene was merged with lsm-2 following advice from the CGC. gut-2 is the main name for this gene. | CGC_data_submission |
| Method | Gene
|