T11G6.1 | SMap | S_parent | Sequence | T11G6
|
| Chromosome | IV |
|
Identity
| Version | 1 |
| |
Name (6)
|
| | Species | Caenorhabditis elegans
|
| | History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971
| Event | Imported | Initial conversion from geneace |
| | Status | Live |
|
Gene_info
| Gene_class | hrs
|
| |
GO_term (7)
|
| | Contained_in_operon | CEOP4396
|
| |
Structured_description
|
Provisional_description
| hrs-1 encodes predicted cytoplasmic and mitochondrial histidyl-tRNA synthetases (HisRS), class II aminoacyl-tRNA synthetases that catalyze the attachment of histidine to its cognate tRNAs and are thus required for protein biosynthesis; HRS-1 synthetases are required for embryogenesis, germline development, wild type body morphology, and normal rates of postembryonic growth. |
Paper_evidence
| WBPaper00004424
|
| | | | | | WBPaper00005654
|
| | | | | Person_evidence | WBPerson1843
|
| | | | | Curator_confirmed | WBPerson1843
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | | This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. |
| | | Concise_description | hrs-1 encodes predicted cytoplasmic and mitochondrial histidyl-tRNA synthetases (HisRS), class II aminoacyl-tRNA synthetases that catalyze the attachment of histidine to its cognate tRNAs and are thus required for protein biosynthesis; HRS-1 synthetases are required for embryogenesis, germline development, wild type body morphology, and normal rates of postembryonic growth. |
|
Molecular_info (5)
|
|
Experimental_info
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RNAi_result
| Cenix:54-e2
|
| | | JA:T11G6.1
|
| | | Simmer:T11G6.1
|
| |
WB_RNAi_result
| JA:T11G6.1
|
| | | Simmer:T11G6.1
|
| | | MV_SV:mv_AAB38116
|
| | | Cenix:54-e2
|
| | Y2H_target | Y2H005979
|
|
Remark
| 2230 nt gene encoding 525 aa predicted protein with extensive similarity to yeast and human histidyl-tRNA synthetases |
| | Data extracted from Amaar and Baillie, 1993 |
| | 1a is cytoplasmic and 1b is mitochondrial based on PSORT, iPSORT and SignalP analysis [030411 ck1] | Curator_confirmed | WBPerson1846
|
| Method | Gene
|