Gene: T16A9.4   

T16A9.4	SMap	S_parent	Sequence	T16A9
	Chromosome	V
	Identity (5)
	Gene_info	Allele	tm755
			snp_T16A9[1]
			snp_T16A9[2]
		GO_term (5)
		Structured_description	Provisional_description	T16A9.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T16A9.4 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).	Paper_evidence	WBPaper00004584
						WBPaper00013276
					Person_evidence	WBPerson567
					Curator_confirmed	WBPerson567
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	T16A9.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T16A9.4 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
	Molecular_info (5)
	Experimental_info	RNAi_result	Cenix:141-c6
			JA:T16A9.4
		WB_RNAi_result	JA:T16A9.4
			MV_SV:mv_T16A9.4
			Cenix:141-c6
	Reference	WBPaper00023670
	Method	Gene

Please provide feedback if you are experiencing any difficulties with this website.