T22E5.5 | SMap | S_parent | Sequence | T22E5
|
| Chromosome | X |
|
Identity (5)
|
|
Gene_info
| Gene_class | mup
|
| |
Allele
| e2346
|
Inferred_automatically
| From strain object: EE31 |
| | | | | From strain object: EE66 |
| | | | | From strain object: EE67 |
| | | up1
|
| | Phenotype | [C.elegansII] e2346ts : embryonic temp-shift leads to lethal mispositioning and deformity of body-wall muscle; larval temp-shift leads to sterility, defects in oviduct muscle. OA1: up1 (non-conditional, lethal with arrest as kinked larva; probable null, nonsense mutation). Cloned: encodes troponin T homolog. [EE; UG] |
| |
Strain
| EE31
|
| | | EE66
|
| | | EE67
|
| |
GO_term
| GO:0006937
|
IMP
| Paper_evidence | WBPaper00003294
|
| | | | | Curator_confirmed | WBPerson48
|
| | | GO:0045214
|
IMP
| Paper_evidence | WBPaper00002414
|
| | | | | Curator_confirmed | WBPerson48
|
| | | GO:0030728
|
IMP
| Paper_evidence | WBPaper00002414
|
| | | | | Curator_confirmed | WBPerson48
|
| | | GO:0005861
|
ISS
| Paper_evidence | WBPaper00002414
|
| | | | | Curator_confirmed | WBPerson48
|
| |
Structured_description
| Provisional_description | mup-2 encodes the muscle contractile protein troponin T ( TnT ) homologous to vertebrate and invertebrate TnT and contains an invertebrate- specific COOH -terminal tail; mup-2 affects embryonic body wall muscle cell contraction, sarcomere organization, cell positioning, regulated muscle contraction in larval and adult body wall muscle, epidermal morphogenesis, and is required for proper function of the hermaphrodite nonstriated oviduct myoepithelial sheath, proper growth, and fertility. |
Paper_evidence
| WBPaper00002414
|
| | | | | | WBPaper00003294
|
| | | | | | WBPaper00006395
|
| | | | | Curator_confirmed | WBPerson48
|
| | | | | Date_last_updated | 11 Mar 2005 00:00:00 |
| | | Concise_description | mup-2 encodes the muscle contractile protein troponin T ( TnT ) homologous to vertebrate and invertebrate TnT and contains an invertebrate- specific COOH -terminal tail; mup-2 affects embryonic body wall muscle cell contraction, sarcomere organization, cell positioning, regulated muscle contraction in larval and adult body wall muscle, epidermal morphogenesis, and is required for proper function of the hermaphrodite nonstriated oviduct myoepithelial sheath, proper growth, and fertility. |
|
Molecular_info (5)
|
|
Experimental_info
|
RNAi_result
| Cenix:62-d10
|
| | | JA:T22E5.5
|
| | | Simmer:T22E5.5:Repeat_a
|
| | | Simmer:T22E5.5:Screen
|
| |
WB_RNAi_result (10)
|
| |
Interaction
| WBInteraction0000340
|
| | | WBInteraction0000746
|
| | | WBInteraction0000747
|
|
Reference (25)
|
| Method | Gene
|