RNAi: TH:302h12   

TH:302h12	RNAi_reagent	TH:302h12
	Method	RNAi
	WormBaseID	WBRNAi00002472
	Reference	WBPaper00004403
	Experiment	Laboratory	TH
		Author (21)
		Date	16 Nov 2000 00:00:00
	Inhibits (5)
	WB_Homol	Homol_homol	C30C11:RNAi
	WB_Uniquely_mapped
	Remark	Phenotype comment -- Confirmed with independent dsRNA (C30C11.2-RNA2; similar phenotype).
		DIC phenotype -- In most embryos (e.g. movie1), the male and female pronuclei never become visible, and everything seems to be arrested. Some embryos progressed to the one cell stage (e.g. movie2): in these cases, there is a sriking delay during mitosis (over 20 min between breakdown of the pronuclear envelopes and cleavage furrow ingression, compared to the usual approximately 2 min in wild-type); earlier events in the one cell stage may be slow as well.
		DIC phenotype comment -- Staining of fixed embryos with DNA dye shows that fertilization took place, and suggests that at least half of the embryos are arrested during meiotic divisions.
		All embryos dead
	Results (2)

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