RNAi: TH:335f3
TH:335f3 | RNAi_reagent | TH:335f3 | |
---|---|---|---|
Method | RNAi | ||
WormBaseID | WBRNAi00002694 | ||
Reference | WBPaper00004403 | ||
Experiment | Laboratory | TH | |
Author (21) | |||
Date | 16 Nov 2000 00:00:00 | ||
Inhibits (9) | |||
WB_Homol | Homol_homol | F58A4:RNAi | |
WB_Uniquely_mapped | |||
Remark | Phenotype comment -- Confirmed with independent dsRNA (K.O., unpublished observations; similar phenotype). Phenotype could potentially be due to cross-RNAi inhibition of other CENP-A like gene (F54C8.2) (see BLASTN results). We note, however, that the phenotypes associated with these two genes are somewhat different, suggesting that the phenotype noted here may truly reflect a requirement for F58A4.3 function. | ||
DIC phenotype -- Daughter nuclei stay close to the central cortex; usually multiple nuclei (karyomeres) in each daughter blastomere. | |||
DIC phenotype comment -- We have shown in separate work (P.G., unpublished observations) that this phenotype is associated with lagging chromosomal material that retains daughter nuclei together at the central cortex. | |||
All embryos dead | |||
Results | Phenotype | Emb | |
Phenotype_summary (7) |