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Gene: W02D3.9   

W02D3.9SMapS_parentSequenceW02D3
ChromosomeI
Identity (5)
Gene_info Gene_classunc
Reference_allele e262
s80
Allele (10)
Phenotype (5)
Strain (9)
GO_term (9)
Contained_in_operonCEOP1348
Structured_description Provisional_description The unc-37 gene encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO that genetically interacts with components of the transcriptional Mediator complex.Paper_evidenceWBPaper00005136
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
unc-37 mutations, in conjunction with mutations in the dpy-22, sop-3, and sur-2 genes, induce synthetic lethality and loss of male sensory neurons.
Null unc-37 mutant homozygotes that escape embryonic and larval lethality show loss of male sensory neurons.
Concise_descriptionThe unc-37 gene encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO that genetically interacts with components of the transcriptional Mediator complex.
Molecular_info (6)
Experimental_info RNAi_result (5)
WB_RNAi_result (6)
Expr_pattern Expr329
Expr2666
Expr5124
Y2H_target (12)
Interaction (22)
Reference (80)
Remark[Miller D and Barnes T] unc-37 encodes a homolog of Drosophila groucho and therefore is likely to function as a transcription cofactor protein.
MethodGene