Gene: W02D3.9
W02D3.9 | SMap | S_parent | Sequence | W02D3 | ||
---|---|---|---|---|---|---|
Chromosome | I | |||||
Identity (5) | ||||||
Gene_info | Gene_class | unc | ||||
Reference_allele | e262 | |||||
s80 | ||||||
Allele (10) | ||||||
Phenotype (5) | ||||||
Strain (9) | ||||||
GO_term (9) | ||||||
Contained_in_operon | CEOP1348 | |||||
Structured_description | Provisional_description | The unc-37 gene encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO that genetically interacts with components of the transcriptional Mediator complex. | Paper_evidence | WBPaper00005136 | ||
Person_evidence | WBPerson567 | |||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
unc-37 mutations, in conjunction with mutations in the dpy-22, sop-3, and sur-2 genes, induce synthetic lethality and loss of male sensory neurons. | ||||||
Null unc-37 mutant homozygotes that escape embryonic and larval lethality show loss of male sensory neurons. | ||||||
Concise_description | The unc-37 gene encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO that genetically interacts with components of the transcriptional Mediator complex. | |||||
Molecular_info (6) | ||||||
Experimental_info | RNAi_result (5) | |||||
WB_RNAi_result (6) | ||||||
Expr_pattern | Expr329 | |||||
Expr2666 | ||||||
Expr5124 | ||||||
Y2H_target (12) | ||||||
Interaction (22) | ||||||
Reference (80) | ||||||
Remark | [Miller D and Barnes T] unc-37 encodes a homolog of Drosophila groucho and therefore is likely to function as a transcription cofactor protein. | |||||
Method | Gene |