The unc-37 gene encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO that genetically interacts with components of the transcriptional Mediator complex.
unc-37 mutations, in conjunction with mutations in the dpy-22, sop-3, and sur-2 genes, induce synthetic lethality and loss of male sensory neurons.
Null unc-37 mutant homozygotes that escape embryonic and larval lethality show loss of male sensory neurons.
Concise_description
The unc-37 gene encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO that genetically interacts with components of the transcriptional Mediator complex.