W03C9.7 | SMap | S_parent | Sequence | SUPERLINK_CB_II
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| Chromosome | II |
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Identity (5)
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Gene_info
| Gene_class | mex
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| | Reference_allele | it9
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Allele (10)
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Phenotype
| [Draper BW] Maternal effect lethal mutation which results in the four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS. This results in embryos which produce excess muscle and pharynx. |
| | | [C.elegansII] zu121 : maternal effect lethal mutation, which results in four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS. This results in embryos which produce excess muscle and pharynx. OA9: zu120, zu122, zu140, zu173, zu221it9 (pka mel-21)[Mello et al. 1992; JJ; KK] |
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Strain
| JJ529
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| | | KK337
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GO_term (7)
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Structured_description
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Provisional_description
| The mex-1 gene encodes a CCCH-type zinc-finger protein that is required maternally for segregation of P granules, germ cell formation, and somatic cell differentiation in the early embryo; mex-1 is expressed cytoplasmically in germ line blastomeres and is required for restricting PIE-1 expression and function to these cells; mex-1 RNA is also found transiently in association with P granules. |
Paper_evidence (5)
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| | | | | Person_evidence | WBPerson1843
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| | | | | Curator_confirmed | WBPerson1843
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| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | | mex-1 is believed to function as a link between cortical polarity established by the par genes and subsequent differential segregation of cytoplasmic determinants. |
| | | Concise_description | The mex-1 gene encodes a CCCH-type zinc-finger protein that is required maternally for segregation of P granules, germ cell formation, and somatic cell differentiation in the early embryo; mex-1 is expressed cytoplasmically in germ line blastomeres and is required for restricting PIE-1 expression and function to these cells; mex-1 RNA is also found transiently in association with P granules. |
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Molecular_info (7)
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Experimental_info
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RNAi_result
| PF:GL1_6A11
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| | | Cenix:50-c2
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| | | Cenix:54-g3
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WB_RNAi_result
| PF:GL1_6A11
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| | | Cenix:50-c2
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| | | Cenix:54-g3
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Expr_pattern
| Expr576
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| | | Expr577
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| | Y2H_target | Y2H011221
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Interaction
| WBInteraction0003116
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| | | WBInteraction0003187
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Reference (85)
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| Method | Gene
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