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Gene: W03C9.7   

W03C9.7SMapS_parentSequenceSUPERLINK_CB_II
ChromosomeII
Identity (5)
Gene_info Gene_classmex
Reference_alleleit9
Allele (10)
Phenotype [Draper BW] Maternal effect lethal mutation which results in the four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS. This results in embryos which produce excess muscle and pharynx.
[C.elegansII] zu121 : maternal effect lethal mutation, which results in four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS. This results in embryos which produce excess muscle and pharynx. OA9: zu120, zu122, zu140, zu173, zu221it9 (pka mel-21)[Mello et al. 1992; JJ; KK]
Strain JJ529
KK337
GO_term (7)
Structured_description Provisional_description The mex-1 gene encodes a CCCH-type zinc-finger protein that is required maternally for segregation of P granules, germ cell formation, and somatic cell differentiation in the early embryo; mex-1 is expressed cytoplasmically in germ line blastomeres and is required for restricting PIE-1 expression and function to these cells; mex-1 RNA is also found transiently in association with P granules. Paper_evidence (5)
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
mex-1 is believed to function as a link between cortical polarity established by the par genes and subsequent differential segregation of cytoplasmic determinants.
Concise_descriptionThe mex-1 gene encodes a CCCH-type zinc-finger protein that is required maternally for segregation of P granules, germ cell formation, and somatic cell differentiation in the early embryo; mex-1 is expressed cytoplasmically in germ line blastomeres and is required for restricting PIE-1 expression and function to these cells; mex-1 RNA is also found transiently in association with P granules.
Molecular_info (7)
Experimental_info (5)
Reference (85)
MethodGene