RNAiDB Tree View

Gene: W06B3.2

W06B3.2	SMap	S_parent	Sequence	SUPERLINK_CB_X
	Chromosome	X
	Identity (5)
	Gene_info	Gene_class	sma
		Reference_allele	n678
		Allele	n678	Paper_evidence	WBPaper00025246
				Inferred_automatically	From strain object: MT1392
					From strain object: MT3353
			tm448
		Phenotype	n678 : very small adult slow-growing; small in L1 and L2. ES3 NA1.
			See also n678
			[C.elegansII] n678 : very small adult, slow-growing; small in L1 and L2. ES3 NA1. [MT]
		Strain	MT1392
			MT3353
		GO_term	GO:0004672	IEA	Inferred_automatically
			GO:0005524	IEA	Inferred_automatically
			GO:0006468	IEA	Inferred_automatically
			GO:0004674	IEA	Inferred_automatically
		Structured_description	Provisional_description	sma-5 encodes a serine/threonine kinase homologous to the mammalian MAP kinase MAPK7/ERK5 (OMIM:602521, required for development of extraembryonic vasculature and embryonic cardiovasculature); SMA-5 is required for normal body size morphogenesis, growth rates, and intestinal granule distribution, and for regulating the size of the intestine, body wall muscle, and hypodermis, as well as the number of intestinal nuclei; SMA-5 is expressed in the intestine and in hypodermal seam cells.	Paper_evidence	WBPaper00015229
						WBPaper00017624
						WBPaper00019616
					Person_evidence	WBPerson1843
					Curator_confirmed	WBPerson1843
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	sma-5 encodes a serine/threonine kinase homologous to the mammalian MAP kinase MAPK7/ERK5 (OMIM:602521, required for development of extraembryonic vasculature and embryonic cardiovasculature); SMA-5 is required for normal body size morphogenesis, growth rates, and intestinal granule distribution, and for regulating the size of the intestine, body wall muscle, and hypodermis, as well as the number of intestinal nuclei; SMA-5 is expressed in the intestine and in hypodermal seam cells.
	Molecular_info (5)
	Experimental_info	RNAi_result	Cenix:62-g12
		WB_RNAi_result	Cenix:62-g12
		Expr_pattern	Expr3269
	Reference (16)
	Method	Gene