RNAiDB Tree View

Gene: W09B12.1

W09B12.1	SMap	S_parent	Sequence	SUPERLINK_RWXR
	Chromosome	X
	Identity (5)
	Gene_info	Gene_class	ace
		Reference_allele	p1000
		Allele (6)
		Phenotype	p1000 : class A acetylcholinesterase reduced 100%; no behavioral phenotype alone (ES1 ME3) but ace-2;ace-1 is uncoordinated (hypercontracted) and ace-2;ace-3;ace-1 is L1 lethal. NA7.
			See also e1572
			[C.elegansII] p1000 : class A acetylcholinesterase reduced 100%; no behavioral phenotype alone (ES1 ME3) but ace-2;ace-1 is uncoordinated (hypercontracted) and ace-2;ace-3;ace-1 is L1 lethal. Mosaic focus in muscle. OA6: e1572 etc.Cloned: sequence predicts 609 aa, 37% identity with Torpedo acetylcholinesterase. p1000 is W99op. [Herman and Kari 1985; Arpagaus et al. 1994; FF]
		Strain (5)
		GO_term (6)
		Structured_description	Provisional_description	ace-1 encodes a class A acetylcholinesterase that functions redundantly with ACE-2 with respect to total class A acetylcholinesterase activity, and that genetically interacts with ace-2 and ace-3; ace-1 is expressed in the body wall muscle, sphincter muscle, head neurons, a few pharyngeal muscle cells, and the diagonal and spicule muscles of the male.	Paper_evidence (6)
					Person_evidence	WBPerson48
					Curator_confirmed	WBPerson48
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	ace-1 encodes a class A acetylcholinesterase that functions redundantly with ACE-2 with respect to total class A acetylcholinesterase activity, and that genetically interacts with ace-2 and ace-3; ace-1 is expressed in the body wall muscle, sphincter muscle, head neurons, a few pharyngeal muscle cells, and the diagonal and spicule muscles of the male.
	Molecular_info (6)
	Experimental_info	RNAi_result	Cenix:76-g4
			JA:W09B12.1
		WB_RNAi_result	JA:W09B12.1
			MV_SV:mv_CAA53080
			Cenix:76-g4
		Expr_pattern	Expr200
			Expr1222
	Reference (60)
	Method	Gene