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RNAi: WBRNAi00059889   

WBRNAi00059889RNAi_reagentprobe_1:F59G1
MethodRNAi
WormBaseIDWBRNAi00059889
ReferenceWBPaper00025031
SpeciesCaenorhabditis elegans
Experiment Author (6)
Date19 Jan 2005 00:00:00
StrainN2
Inhibits WB_Predicted_geneF59G1.7 Inferred_automaticallyRNAi_primary
WB_GeneF59G1.7 Inferred_automaticallyRNAi_primary
Gene_targetF59G1.7 WormbaseBLASTBLAST_wormbase_primary
WB_HomolHomol_homolF59G1:RNAi
WB_Uniquely_mapped
DeliveryDelivered_byInjection
Results Phenotype Abnormal coloration Remarkpale
Age Remarkfrh-1 RNAi increased mean lifespan by about 25%. Mean lifespan for frh-1 RNAi animals was 20.6 +- 1.0 days (140 animals) vs. 16.5 +- 0.4 days (139 animals) for control RNAi animals (P = 0.00017).
Sma
Stress Resistance RemarkAnimals were exposed for 8 h to 10 mM of hydrogen peroxide and for 2 h to 250 mkM juglone. frh-1 RNAi animals were relatively resistant to hydrogen peroxide, but were more sensitive to juglone, as compared with control RNAi animals.
Phenotype_summary (7)