Gene: Y116A8C.32   

Y116A8C.32	SMap	S_parent	Sequence	Y116A8C
	Chromosome	IV
	Identity (5)
	Gene_info	GO_term	GO:0003676	IEA	Inferred_automatically
		Contained_in_operon	CEOP4596
		Structured_description	Provisional_description	Y116A8C.32 encodes an ortholog of splicing factor SF1, which enables 3' splice site recognition by binding U2AF65 and the intron branch site during splicing complex formation; Y116A8C.32 shares several domains with mammalian SF1 proteins (a U2AF65 binding domain, a hnRNP K homology domain, two RNA-binding zinc knuckles, and a proline-rich C-terminal domain), while also sharing a hydrophilic N-terminal domain (enriched for serine, arginine, lysine, and aspartate) with Drosophila but not mammalian SF1; Y116A8C.32's N-terminal domain resembles RS domains in other splicing proteins; Y116A8C.32 is required for embryonic viability, normally rapid growth, and proper body morphology.	Paper_evidence	WBPaper00003817
						WBPaper00005654
					Person_evidence	WBPerson71
					Curator_confirmed	WBPerson71
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	Y116A8C.32 encodes an ortholog of splicing factor SF1, which enables 3' splice site recognition by binding U2AF65 and the intron branch site during splicing complex formation; Y116A8C.32 shares several domains with mammalian SF1 proteins (a U2AF65 binding domain, a hnRNP K homology domain, two RNA-binding zinc knuckles, and a proline-rich C-terminal domain), while also sharing a hydrophilic N-terminal domain (enriched for serine, arginine, lysine, and aspartate) with Drosophila but not mammalian SF1; Y116A8C.32's N-terminal domain resembles RS domains in other splicing proteins; Y116A8C.32 is required for embryonic viability, normally rapid growth, and proper body morphology.
	Molecular_info (6)
	Experimental_info (2)
	Reference	WBPaper00003817
	Method	Gene

Please provide feedback if you are experiencing any difficulties with this website.