Gene: Y22D7AL.5
Y22D7AL.5 | Evidence | Paper_evidence | WBPaper00005851 | |||
---|---|---|---|---|---|---|
SMap | S_parent | Sequence | Y22D7AL | |||
Chromosome | III | |||||
Identity (5) | ||||||
Gene_info | Gene_class | hsp | ||||
Allele (5) | ||||||
GO_term (3) | ||||||
Structured_description | Provisional_description | hsp-60 encodes a mitochondrial-specific chaperone that is a member of the GroE/Hsp10/60 superfamily of molecular chaperones; hsp-60 is believed to be involved in the mitochondrial unfolded protein response, as hsp-60 expression, normally broadly detected during development, is greatly increased in response to treatments that disrupt mitochondrial protein handling; loss of hsp-60 activity via RNAi results in severe growth defects with arrest at embryonic and early larval stages of development. | Paper_evidence | WBPaper00024269 | ||
Person_evidence | WBPerson1843 | |||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 07 Jan 2005 00:00:00 | |||||
hsp-60 is nuclear-encoded. | ||||||
Concise_description | hsp-60 encodes a mitochondrial-specific chaperone that is a member of the GroE/Hsp10/60 superfamily of molecular chaperones; hsp-60 is believed to be involved in the mitochondrial unfolded protein response, as hsp-60 expression, normally broadly detected during development, is greatly increased in response to treatments that disrupt mitochondrial protein handling; loss of hsp-60 activity via RNAi results in severe growth defects with arrest at embryonic and early larval stages of development. | |||||
Molecular_info (5) | ||||||
Experimental_info | RNAi_result | Cenix:177-b5 | ||||
WB_RNAi_result | MV_SV:mv_AAA28077 | |||||
Cenix:177-b5 | ||||||
Gene_regulation | Trans_target | cgc6848_hsp-60 | ||||
Reference | WBPaper00024269 | |||||
WBPaper00024340 | ||||||
WBPaper00026640 | ||||||
Method | Gene |