RNAiDB Tree View

Gene: Y24D9A.4

Y24D9A.4	SMap	S_parent	Sequence	Y24D9A
	Chromosome	IV
	Identity (5)
	Gene_info	Gene_class	rpl
		Phenotype	Orthologous to yeast (S.cerevisiae) ribosomal protein rpl8 using blastP
		GO_term (6)
		Structured_description	Provisional_description	rpl-8 encodes a large ribosomal subunit L7a protein required in mass RNAi assays for fertility, vulval development, and general health; the rpl-8 transcription unit has one nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-8 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-10, rpl-12) have protein products that are involved in translation.	Paper_evidence	WBPaper00004313
						WBPaper00005654
						WBPaper00006395
					Person_evidence	WBPerson567
					Curator_confirmed	WBPerson567
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	rpl-8 encodes a large ribosomal subunit L7a protein required in mass RNAi assays for fertility, vulval development, and general health; the rpl-8 transcription unit has one nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-8 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-10, rpl-12) have protein products that are involved in translation.
	Molecular_info (6)
	Experimental_info	RNAi_result	Cenix:143-a10
			JA:Y24D9A.d
			Simmer:Y24D9A.d
		WB_RNAi_result (6)
		Expr_pattern	Expr5742
	Remark	data taken from http://www.sanger.ac.uk/Projects/C_elegans/ANNOTATION/ribosomal_protein/
		This gene previously was known as rpl-8 with rpl-7A as an other name. Following advice from the CGC, this situation has been reversed and rpl-7A is now the main (CGC approved) name for this gene [040706 krb]
	Method	Gene