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Gene: Y38F2AL.1   

Y38F2AL.1SMapS_parentSequenceY38F2AL
ChromosomeIV
Identity (5)
Gene_info GO_termGO:0016021 IEA Inferred_automatically
Structured_description Provisional_descriptionY38F2AL.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; Y38F2AL.1 is worm-specific, with obvious homologs only in C. elegans; Y38F2AL.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. Paper_evidence (7)
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionY38F2AL.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; Y38F2AL.1 is worm-specific, with obvious homologs only in C. elegans; Y38F2AL.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
Molecular_info (5)
Experimental_info RNAi_result (5)
WB_RNAi_result (6)
MethodGene