RNAiDB Tree View

Gene: Y43F4B.6

Y43F4B.6	SMap	S_parent	Sequence	Y43F4B
	Chromosome	III
	Identity (5)
	Gene_info	Gene_class	klp
		Allele	bn126	Inferred_automatically	From strain object: SS746
		Strain	SS746
		GO_term	GO:0003777	IEA	Inferred_automatically
			GO:0005524	IEA	Inferred_automatically
			GO:0007018	IEA	Inferred_automatically
			GO:0005875	IEA	Inferred_automatically
		Structured_description	Provisional_description	klp-19 encodes a plus-end-directed microtubule motor protein that is most closely related to motors of the kinesin-4 family; KLP-19 activity is essential for embryonic and larval development and is required for generating a force that aligns sister chromatid kinetochores directly opposite the spindle poles thus ensuring proper holocentric chromosome segregation; KLP-19 expression is detected in embryos and in the gonad, where it is most strongly expressed in distal mitotic nuclei and in late meiotic prophase nucleoplasm; during meiosis and mitosis, KLP-19 expression is dynamic and is detected in the nucleoplasm, the spindle body, in association with condensed chromosomes (particularly between homologous chromosomes), and in the spindle interzone.	Paper_evidence	WBPaper00024405
					Person_evidence	WBPerson1843
					Curator_confirmed	WBPerson1843
					Date_last_updated	05 Jan 2005 00:00:00
			Concise_description	klp-19 encodes a plus-end-directed microtubule motor protein that is most closely related to motors of the kinesin-4 family; KLP-19 activity is essential for embryonic and larval development and is required for generating a force that aligns sister chromatid kinetochores directly opposite the spindle poles thus ensuring proper holocentric chromosome segregation; KLP-19 expression is detected in embryos and in the gonad, where it is most strongly expressed in distal mitotic nuclei and in late meiotic prophase nucleoplasm; during meiosis and mitosis, KLP-19 expression is dynamic and is detected in the nucleoplasm, the spindle body, in association with condensed chromosomes (particularly between homologous chromosomes), and in the spindle interzone.
	Molecular_info (5)
	Experimental_info	RNAi_result (7)
		WB_RNAi_result (8)
		Expr_pattern	Expr3116
		Y2H_bait	Y2H003130
	Reference (5)
	Remark	Sequence connection from [Siddiqui SS], 02/06/11 krb.
		Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene