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Gene: Y46H3A.2   

Y46H3A.2SMapS_parentSequenceY46H3A
ChromosomeV
Identity (5)
Gene_info Gene_classhsp
Alleletm1093
In_clusterHSP16B
Structured_description Provisional_description hsp-16.41 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; an hsp-16.41 reporter fusion, expressed broadly but strongest in intestine and pharynx, is induced in response to heat shock or other environmental stresses; expression is detectable in somatic tissues in post-gastrulation embryos, all larval stages, and in adults; HSP-16.41 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating. Paper_evidence (7)
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated05 Nov 2004 00:00:00
In general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.
Concise_descriptionhsp-16.41 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; an hsp-16.41 reporter fusion, expressed broadly but strongest in intestine and pharynx, is induced in response to heat shock or other environmental stresses; expression is detectable in somatic tissues in post-gastrulation embryos, all larval stages, and in adults; HSP-16.41 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating.
Molecular_info (5)
Experimental_info RNAi_result Cenix:242-f10
JA:Y46H3A.e
WB_RNAi_result JA:Y46H3A.e
MV_SV:mv_AAA28069
MV_SV:mv_AAA28070
Cenix:242-f10
Expr_pattern Expr1381
Expr1388
Reference (8)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene