RNAiDB Tree View

Gene: Y47G6A.20

Y47G6A.20	Evidence	Person_evidence	WBPerson71
			WBPerson395
	SMap	S_parent	Sequence	Y47G6A
	Chromosome	I
	Identity (5)
	Gene_info	Gene_class	rnp
		GO_term	GO:0000166	IEA	Inferred_automatically
			GO:0003676	IEA	Inferred_automatically
		Structured_description	Provisional_description	rnp-6 encodes an ortholog of HALF-PINT in D. melanogaster and FBP Interacting Repressor (FIR)/PUF60 in mammals, predicted to be involved in mRNA splicing regulation, mRNA localization, or transcriptional regulation via TFIIH.	Paper_evidence	WBPaper00012787
						WBPaper00012860
						WBPaper00013021
					Person_evidence	WBPerson567
					Curator_confirmed	WBPerson567
					Date_last_updated	17 Jun 2004 00:00:00
				HALF-PINT regulates RNA splicing, is required for normal RNA localization during oogenesis, functions in both constitutive and alternative splicing in vivo, and is specifically required in vivo for a developmentally regulated splice form of the ovarian tumor gene.
				FBP Interacting Repressor (FIR)/PUF60 blocks the transcriptional activation of c-myc by FUSE binding protein, via TFIIH subunits p62, p89, and Cyclin H, and, at the same time, enables the binding of U2 snRNP to pre-mRNA in conjunction with the large subunit of U2AF, U2AF65.
			Concise_description	rnp-6 encodes an ortholog of HALF-PINT in D. melanogaster and FBP Interacting Repressor (FIR)/PUF60 in mammals, predicted to be involved in mRNA splicing regulation, mRNA localization, or transcriptional regulation via TFIIH.
	Molecular_info	Corresponding_CDS	Y47G6A.20a
			Y47G6A.20b
			Y47G6A.20c
		Corresponding_protein	WP:CE24365
			WP:CE24366
			WP:CE31375
		Corresponding_PCR_product	sjj_Y47G6A_245.f
			sjj_Y47G6A_245.g
		Corresponding_RNAi_reagent	Cenix:90-g11
			sjj_Y47G6A_245.f
			sjj_Y47G6A_245.g
			mv_Y47G6A.20a
	Experimental_info	RNAi_result (6)
		WB_RNAi_result	JA:Y47G6A_245.f
			JA:Y47G6A_245.g
			Simmer:Y47G6A_245.f:Repeat_b
			Simmer:Y47G6A_245.f:Screen_A
			Simmer:Y47G6A_245.f:Screen_B
			MV_SV:mv_Y47G6A.20a
			Cenix:90-g11
	Method	Gene