| | | [C.elegansII] e2123ts : at 25C zygotic embryonic lethal, pharynx fails to undergo late differentiation and morphogenesis; early pharynx development normal. OA>5: e2468 (unconditional), t1001ts,e2286 (weak, 38% hatch and arrest), t1002 (weak,some survival to late larval arrest), etc.See also extragenic suppressors sup-35, sup-36, sup-37. Cloned: 2.2kb embryonic transcript, encodes 491 aa predicted protein with some similarity to bZIP transcription factors; pha-1:lacZ expressed transiently in all pharyngeal precursor cells. [Granato et al. 1994; GE] |
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