Y49E10.14 | SMap | S_parent | Sequence | Y49E10
|
| Chromosome | III |
|
Identity (5)
|
|
Gene_info
| Gene_class | pie
|
| |
Allele
| t1682
|
| | | zu127
|
| | | zu154
|
Inferred_automatically
| From strain object: EU16 |
| | | | | From strain object: JJ532 |
| | | zu177
|
| | Phenotype | [C.elegansII] zu154 : maternal effect lethal, often with two distinct pharynges; additional pharynx and intestinal tissue from P2 (transformed to EMS fate).OA1. Cloned: encodes zinc finger protein, localized to nuclei of germ line blastomeres. [Mello et al. 1992; Mango et al. 1994; EU; JJ] |
| |
Strain (11)
|
| |
GO_term (8)
|
| |
Structured_description
|
Provisional_description
| pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6. |
Paper_evidence (7)
|
| | | | | Person_evidence | WBPerson1843
|
| | | | | Curator_confirmed | WBPerson1843
|
| | | | | Date_last_updated | 30 Nov 2004 00:00:00 |
| | | | PIE-1 regulates both zygotic and materal gene expresssion in the embryonic germ line; in germ cells, PIE-1 is required for efficient expression of nos-2. |
| | | Concise_description | pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6. |
|
Molecular_info (7)
|
|
Experimental_info (6)
|
|
Reference (198)
|
| Method | Gene
|