Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: Y49E10.14   

Y49E10.14SMapS_parentSequenceY49E10
ChromosomeIII
Identity (5)
Gene_info Gene_classpie
Allele t1682
zu127
zu154 Inferred_automatically From strain object: EU16
From strain object: JJ532
zu177
Phenotype[C.elegansII] zu154 : maternal effect lethal, often with two distinct pharynges; additional pharynx and intestinal tissue from P2 (transformed to EMS fate).OA1. Cloned: encodes zinc finger protein, localized to nuclei of germ line blastomeres. [Mello et al. 1992; Mango et al. 1994; EU; JJ]
Strain (11)
GO_term (8)
Structured_description Provisional_description pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6. Paper_evidence (7)
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated30 Nov 2004 00:00:00
PIE-1 regulates both zygotic and materal gene expresssion in the embryonic germ line; in germ cells, PIE-1 is required for efficient expression of nos-2.
Concise_descriptionpie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6.
Molecular_info (7)
Experimental_info (6)
Reference (198)
MethodGene