Gene: Y54E5B.3
Y54E5B.3 | SMap | S_parent | Sequence | Y54E5B | ||
---|---|---|---|---|---|---|
Chromosome | I | |||||
Identity (5) | ||||||
Gene_info | Gene_class | let | ||||
Reference_allele | st44 | |||||
Allele | st44 | Inferred_automatically | From strain object: RW3199 | |||
Phenotype | st44 : mid-larval lethal. NA1. | |||||
[C.elegansII] st44 : mid-larval lethal. NA1. [Anderson and Brenner 1984; RW] | ||||||
Strain | RW3199 | |||||
GO_term | GO:0003713 | IEA | Inferred_automatically | |||
GO:0045941 | IEA | Inferred_automatically | ||||
GO:0005634 | IEA | Inferred_automatically | ||||
Contained_in_operon | CEOP1768 | |||||
Structured_description | Provisional_description | let-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1. | Paper_evidence (5) | |||
Person_evidence | WBPerson567 | |||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
Concise_description | let-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1. | |||||
Molecular_info (5) | ||||||
Experimental_info | RNAi_result | JA:Y54E5B.3 | ||||
Simmer:Y54E5B.3:Screen_A | ||||||
Simmer:Y54E5B.3:Screen_B | ||||||
Cenix:34-c8 | ||||||
WB_RNAi_result | JA:Y54E5B.3 | |||||
Simmer:Y54E5B.3:Screen_A | ||||||
Simmer:Y54E5B.3:Screen_B | ||||||
MV_SV:mv_Y54E5B.3 | ||||||
Cenix:34-c8 | ||||||
Reference (8) | ||||||
Method | Gene |