Gene: Y56A3A.13
Y56A3A.13 | SMap | S_parent | Sequence | Y56A3A | ||
---|---|---|---|---|---|---|
Chromosome | III | |||||
Identity (5) | ||||||
Gene_info | Gene_class | nft | ||||
Contained_in_operon | CEOP3744 | |||||
Structured_description | Provisional_description | The nft-1 gene encodes an ortholog of human FHIT, which when mutated is associated with head and neck cancers (OMIM:601153). | Paper_evidence | WBPaper00004103 | ||
WBPaper00012802 | ||||||
WBPaper00013573 | ||||||
Person_evidence | WBPerson567 | |||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
Heterozygous mutation of the mouse FHIT gene, combined with a tumor-promoting chemical, leads to a mixture of adenomas, squamous paillomas, invasive carcinomas of the forestomach, and tumors of sebaceous glands. | ||||||
The FHIT protein itself is an diadenosine-5',5'''-P(1),P(3)-triphosphate (AP3A) hydrolase (EC 3.6.1.29) that has been proposed to regulate DNA replication or signal stress responses. | ||||||
Concise_description | The nft-1 gene encodes an ortholog of human FHIT, which when mutated is associated with head and neck cancers (OMIM:601153). | |||||
Molecular_info (6) | ||||||
Experimental_info | RNAi_result | Cenix:332-f1 | ||||
TH:332F1 | ||||||
WB_RNAi_result (3) | ||||||
Expr_pattern | Expr5961 | |||||
Y2H_target | Y2H001807 | |||||
Y2H001810 | ||||||
Reference | WBPaper00003154 | |||||
WBPaper00004320 | ||||||
Remark | Y56A3A.V changed to .13 following from sequence annotation. [sdm 05/00] | |||||
Method | Gene |