Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: Y77E11A.4   

Y77E11A.4SMapS_parentSequenceY77E11A
ChromosomeIV
Identity (5)
Gene_info Gene_classjtr
GO_termGO:0016021 IEA Inferred_automatically
Structured_description Provisional_description jtr-1 encodes a predicted transmembrane protein that is related to the conserved jumping translocation breakpoint (JTB) family of proteins (OMIM:604671, the human JTB gene is found fused to telomeric repeats in a case of jumping translocation leading to leukemia); as loss of jtr-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of JTR-1 in C. elegans development and/or behavior is not yet known. Paper_evidence WBPaper00005654
WBPaper00012804
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
In mammals, the JTB homologue is androgen regulated, expressed ubiquitously in normal tissues, and when overexpressed can promote malignancy.
The human JTB gene resides in a region of chromosome 1q21 known as the epidermal differentiation complex, that contains several genes involved in terminal differentiation of the epidermis.
Concise_descriptionjtr-1 encodes a predicted transmembrane protein that is related to the conserved jumping translocation breakpoint (JTB) family of proteins (OMIM:604671, the human JTB gene is found fused to telomeric repeats in a case of jumping translocation leading to leukemia); as loss of jtr-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of JTR-1 in C. elegans development and/or behavior is not yet known.
Molecular_info (5)
Experimental_info RNAi_result Cenix:92-e2
JA:Y77E11A_3443.b
WB_RNAi_result JA:Y77E11A_3443.b
MV_SV:mv_Y77E11A.4
Cenix:92-e2
MethodGene