Y77E11A.4 | SMap | S_parent | Sequence | Y77E11A
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| Chromosome | IV |
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Identity (5)
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Gene_info
| Gene_class | jtr
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| | GO_term | GO:0016021
| IEA
| Inferred_automatically |
| |
Structured_description
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Provisional_description
| jtr-1 encodes a predicted transmembrane protein that is related to the conserved jumping translocation breakpoint (JTB) family of proteins (OMIM:604671, the human JTB gene is found fused to telomeric repeats in a case of jumping translocation leading to leukemia); as loss of jtr-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of JTR-1 in C. elegans development and/or behavior is not yet known. |
Paper_evidence
| WBPaper00005654
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| | | | | | WBPaper00012804
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| | | | | Person_evidence | WBPerson1843
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| | | | | Curator_confirmed | WBPerson1843
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| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | | In mammals, the JTB homologue is androgen regulated, expressed ubiquitously in normal tissues, and when overexpressed can promote malignancy. |
| | | | The human JTB gene resides in a region of chromosome 1q21 known as the epidermal differentiation complex, that contains several genes involved in terminal differentiation of the epidermis. |
| | | Concise_description | jtr-1 encodes a predicted transmembrane protein that is related to the conserved jumping translocation breakpoint (JTB) family of proteins (OMIM:604671, the human JTB gene is found fused to telomeric repeats in a case of jumping translocation leading to leukemia); as loss of jtr-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of JTR-1 in C. elegans development and/or behavior is not yet known. |
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Molecular_info (5)
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Experimental_info
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RNAi_result
| Cenix:92-e2
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| | | JA:Y77E11A_3443.b
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| |
WB_RNAi_result
| JA:Y77E11A_3443.b
|
| | | MV_SV:mv_Y77E11A.4
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| | | Cenix:92-e2
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| Method | Gene
|