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Gene: Y92C3B.2   

Y92C3B.2SMapS_parentSequenceY92C3B
ChromosomeIII
Identity (5)
Gene_info Gene_classuaf
Allelegk392 Inferred_automaticallyFrom strain object: VC720
StrainVC720
GO_term (8)
Contained_in_operonCEOP3052
Structured_description Provisional_descriptionuaf-1 encodes the large subunit of U2AF, the U2 small nuclear ribonucleoparticle (snRNP) auxiliary factor and is a homolog of mammalian and fly U2AF65; UAF-1 has been shown to bind RNA and this binding is enhanced by UAF-2; the abundance of one alternative transcript appears to be increased during starvation and this transcript is retained in the nucleus; uaf-1 affects embryonic viability, based on RNAi analysis. Paper_evidence WBPaper00002652
WBPaper00003463
WBPaper00003474
WBPaper00003836
Person_evidenceWBPerson48
Curator_confirmedWBPerson48
Date_last_updated07 Jan 2005 00:00:00
Concise_descriptionuaf-1 encodes the large subunit of U2AF, the U2 small nuclear ribonucleoparticle (snRNP) auxiliary factor and is a homolog of mammalian and fly U2AF65; UAF-1 has been shown to bind RNA and this binding is enhanced by UAF-2; the abundance of one alternative transcript appears to be increased during starvation and this transcript is retained in the nucleus; uaf-1 affects embryonic viability, based on RNAi analysis.
Sequence_features uaf-1 encodes the large subunit of U2AF, the U2 small nuclear ribonucleoparticle (snRNP) auxiliary factor.Paper_evidenceWBPaper00002652
Curator_confirmedWBPerson48
UAF-1 is a homolog of mammalian and fly U2AF65.Paper_evidenceWBPaper00003474
Curator_confirmedWBPerson48
Functional_pathwayuaf-1 affects embryonic viability, based on RNAi analysis.Paper_evidenceWBPaper00003463
Curator_confirmedWBPerson48
Functional_physical_interactionUAF-1 has been shown to bind DNA and this binding is enhanced by UAF-2.Paper_evidenceWBPaper00003836
Curator_confirmedWBPerson48
ExpressionThe abundance of one alternative transcript for uaf-1 appears to be increased during starvation and this transcript is retained in the nucleus.Paper_evidenceWBPaper00003474
Curator_confirmedWBPerson48
Molecular_info Corresponding_CDS Y92C3B.2a
Y92C3B.2b
Y92C3B.2c
Y92C3B.2d
Corresponding_protein WP:CE25626
WP:CE27339
WP:CE29149
WP:CE30403
KOGKOG0120
Corresponding_RNAi_reagent Cenix:191-g9
mv_AAC26982
Experimental_info RNAi_resultCenix:191-g9
WB_RNAi_result MV_SV:mv_AAC26982
Cenix:191-g9
Expr_patternExpr1616
Y2H_bait (75)
Y2H_targetY2H008297
Reference (7)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene