ZC168.4 | SMap | S_parent | Sequence | ZC168
|
| Chromosome | IV |
|
Identity (5)
|
|
Gene_info
| Gene_class | cyb
|
| | Allele | gk35
|
Inferred_automatically
| From strain object: VC49 |
| | | | | From strain object: VC50 |
| | Phenotype | [C.elegansII] NMK. 72% identity to sea urchin cyclin B. [KB] |
| |
Strain
| VC49
|
| | | VC50
|
| |
GO_term
| GO:0000074
| IEA
| Inferred_automatically |
| | | GO:0005634
| IEA
| Inferred_automatically |
| |
Structured_description
|
Provisional_description
| cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. |
Paper_evidence
| WBPaper00010444
|
| | | | | | WBPaper00018070
|
| | | | | Person_evidence | WBPerson567
|
| | | | | Curator_confirmed | WBPerson567
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | | Combined cyb-1(RNAi) and cyb-3(RNAi) cause embryonic arrest upon meeting of the pronuclei at the one-cell stage, following abnormal meiosis, pseudocleavage and/or pronuclear migrations; this phenotype is more severe than cyb-1(RNAi) or cyb-3(RNAi) alone, and suggests that CYB-1 and CYB-3 exert overlapping functions. |
| | | Concise_description | cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. |
|
Molecular_info (5)
|
|
Experimental_info
|
RNAi_result
| Cenix:10-e7
|
| | | JA:ZC168.4
|
| | | PF:GL1_4C6
|
| |
WB_RNAi_result (11)
|
| | Expr_pattern | Expr3273
|
| | Gene_regulation | Trans_target | cgc6085_cyb-1
|
|
Reference (8)
|
|
Remark
| Sequence connection from [Xu H, Bennett KL] |
| | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene
|