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Gene: ZC168.4   

ZC168.4SMapS_parentSequenceZC168
ChromosomeIV
Identity (5)
Gene_info Gene_classcyb
Allelegk35 Inferred_automatically From strain object: VC49
From strain object: VC50
Phenotype[C.elegansII] NMK. 72% identity to sea urchin cyclin B. [KB]
Strain VC49
VC50
GO_term GO:0000074 IEA Inferred_automatically
GO:0005634 IEA Inferred_automatically
Structured_description Provisional_description cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. Paper_evidence WBPaper00010444
WBPaper00018070
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Combined cyb-1(RNAi) and cyb-3(RNAi) cause embryonic arrest upon meeting of the pronuclei at the one-cell stage, following abnormal meiosis, pseudocleavage and/or pronuclear migrations; this phenotype is more severe than cyb-1(RNAi) or cyb-3(RNAi) alone, and suggests that CYB-1 and CYB-3 exert overlapping functions.
Concise_descriptioncyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage.
Molecular_info (5)
Experimental_info RNAi_result Cenix:10-e7
JA:ZC168.4
PF:GL1_4C6
WB_RNAi_result (11)
Expr_patternExpr3273
Gene_regulationTrans_targetcgc6085_cyb-1
Reference (8)
Remark Sequence connection from [Xu H, Bennett KL]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene