Gene: ZC168.4
ZC168.4 | SMap | S_parent | Sequence | ZC168 | ||
---|---|---|---|---|---|---|
Chromosome | IV | |||||
Identity (5) | ||||||
Gene_info | Gene_class | cyb | ||||
Allele | gk35 | Inferred_automatically | From strain object: VC49 | |||
From strain object: VC50 | ||||||
Phenotype | [C.elegansII] NMK. 72% identity to sea urchin cyclin B. [KB] | |||||
Strain | VC49 | |||||
VC50 | ||||||
GO_term | GO:0000074 | IEA | Inferred_automatically | |||
GO:0005634 | IEA | Inferred_automatically | ||||
Structured_description | Provisional_description | cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. | Paper_evidence | WBPaper00010444 | ||
WBPaper00018070 | ||||||
Person_evidence | WBPerson567 | |||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
Combined cyb-1(RNAi) and cyb-3(RNAi) cause embryonic arrest upon meeting of the pronuclei at the one-cell stage, following abnormal meiosis, pseudocleavage and/or pronuclear migrations; this phenotype is more severe than cyb-1(RNAi) or cyb-3(RNAi) alone, and suggests that CYB-1 and CYB-3 exert overlapping functions. | ||||||
Concise_description | cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. | |||||
Molecular_info (5) | ||||||
Experimental_info | RNAi_result | Cenix:10-e7 | ||||
JA:ZC168.4 | ||||||
PF:GL1_4C6 | ||||||
WB_RNAi_result (11) | ||||||
Expr_pattern | Expr3273 | |||||
Gene_regulation | Trans_target | cgc6085_cyb-1 | ||||
Reference | WBPaper00004349 | |||||
WBPaper00010444 | ||||||
WBPaper00018070 | ||||||
WBPaper00019701 | ||||||
WBPaper00024430 | ||||||
WBPaper00024321 | ||||||
WBPaper00025987 | ||||||
WBPaper00026430 | ||||||
Remark | Sequence connection from [Xu H, Bennett KL] | |||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |