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Gene: ZC482.1   

ZC482.1SMapS_parentSequenceZC482
ChromosomeIII
Identity (5)
Gene_info Gene_classgab
Phenotype[C.elegansII] NMK. Cross-hybridization to GABA receptor probe. [CGC]
GO_term (11)
Structured_description Provisional_descriptiongab-1 encodes a gamma-aminobutyric acid (GABA) receptor beta-like subunit with both the neurotransmitter-gated ion-channel ligand binding and transmembrane domains; gab-1 can form a GABA-responsive channel when co-expressed with alpha/gamma type subunits in a heterologous expression system; experiments with gab-1 indicate that GABA receptors are involved in the mechanism of resistance to the widely used broad-spectrum anthelmintic drug Ivermectin.Paper_evidenceWBPaper00005574
Person_evidenceWBPerson324
Curator_confirmedWBPerson324
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptiongab-1 encodes a gamma-aminobutyric acid (GABA) receptor beta-like subunit with both the neurotransmitter-gated ion-channel ligand binding and transmembrane domains; gab-1 can form a GABA-responsive channel when co-expressed with alpha/gamma type subunits in a heterologous expression system; experiments with gab-1 indicate that GABA receptors are involved in the mechanism of resistance to the widely used broad-spectrum anthelmintic drug Ivermectin.
Molecular_info (6)
Experimental_info RNAi_result Cenix:323-e11
JA:ZC482.1
TH:323E11
WB_RNAi_result TH:323E11
JA:ZC482.1
MV_SV:mv_ZC482.1
Cenix:323-e11
Reference WBPaper00003954
WBPaper00006402
MethodGene