ZC482.1 | SMap | S_parent | Sequence | ZC482
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| Chromosome | III |
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Identity (5)
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Gene_info
| Gene_class | gab
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| | Phenotype | [C.elegansII] NMK. Cross-hybridization to GABA receptor probe. [CGC] |
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GO_term (11)
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Structured_description
| Provisional_description | gab-1 encodes a gamma-aminobutyric acid (GABA) receptor beta-like subunit with both the neurotransmitter-gated ion-channel ligand binding and transmembrane domains; gab-1 can form a GABA-responsive channel when co-expressed with alpha/gamma type subunits in a heterologous expression system; experiments with gab-1 indicate that GABA receptors are involved in the mechanism of resistance to the widely used broad-spectrum anthelmintic drug Ivermectin. | Paper_evidence | WBPaper00005574
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| | | | | Person_evidence | WBPerson324
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| | | | | Curator_confirmed | WBPerson324
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| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Concise_description | gab-1 encodes a gamma-aminobutyric acid (GABA) receptor beta-like subunit with both the neurotransmitter-gated ion-channel ligand binding and transmembrane domains; gab-1 can form a GABA-responsive channel when co-expressed with alpha/gamma type subunits in a heterologous expression system; experiments with gab-1 indicate that GABA receptors are involved in the mechanism of resistance to the widely used broad-spectrum anthelmintic drug Ivermectin. |
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Molecular_info (6)
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Experimental_info
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RNAi_result
| Cenix:323-e11
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| | | JA:ZC482.1
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| | | TH:323E11
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WB_RNAi_result
| TH:323E11
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| | | JA:ZC482.1
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| | | MV_SV:mv_ZC482.1
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| | | Cenix:323-e11
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Reference
| WBPaper00003954
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| | WBPaper00006402
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| Method | Gene
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