RNAiDB Tree View

Gene: ZK154.3

ZK154.3	SMap	S_parent	Sequence	ZK154
	Chromosome	X
	Identity	Version	1
		Name (7)
		Species	Caenorhabditis elegans
		History	Version_change	1	07 Apr 2004 11:29:31	WBPerson1971	Event	Imported	Initial conversion from geneace
		Status	Live
	Gene_info	Gene_class	mec
		Reference_allele	e1343
		Allele (18)
		Phenotype	e1343sd ts : touch insensitive lethargic at 25x; microtubule cells lack microtubules; e1343/+ variably touch insensitive at 25x; wildtype at 15x. ES2 ME3. NA > 30 (n434dm (dominant at all temperatures) e1506 (recessive at all temperatures) etc.). Most alleles incompletely dominant and ts.
			See also e1343, e1477, n434
			[C.elegansII] e1343sd,ts : touch insensitive, lethargic at 25C; microtubule cells lack 15-protofilament microtubules; e1343/+ variably touch insensitive at 25C; wildtype at 15C. ES2 ME3. OA>30:n434dm (dominant at all temperatures), e1506 (recessive at all temperatures), e1527,u278 (missense, causes ectopic touch cell branching),u443 (deletion null), etc. Most alleles incompletely dominant and ts. Cloned: encodes beta-tubulin. Antibody stains strongly in touch cells, weakly in some others (FLP, PVD). 45 alleles sequenced. [Savage et al. 1989; Hamelin et al. 1992; NW; TU]
		Strain (11)
		GO_term (13)
		Structured_description	Provisional_description	mec-7 encodes a beta-tubulin required for touch sensitivity along the body wall, and for normal levels of locomotor activity; it is strongly expressed in six touch receptor neurons, with weak expression in FLP, PVD, and BDU cells.	Person_evidence	WBPerson48
					Curator_confirmed	WBPerson48
			Concise_description	mec-7 encodes a beta-tubulin required for touch sensitivity along the body wall, and for normal levels of locomotor activity; it is strongly expressed in six touch receptor neurons, with weak expression in FLP, PVD, and BDU cells.
	Molecular_info (5)
	Experimental_info	RNAi_result	Cenix:217-d8
		WB_RNAi_result (12)
		Expr_pattern	Expr266
			Expr1504
			Expr1524
			Expr1577
		Interaction (23)
	Reference (179)
	Method	Gene