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Gene: ZK354.5   

ZK354.5SMapS_parentSequenceZK354
ChromosomeIV
Identity (5)
Gene_info Gene_classmsp
Phenotype[C.elegansII] NMK. Encodes MSP (16kD); msp-113 cluster. [Ward et al. (1988); BA]
GO_termGO:0005198 IEA Inferred_automatically
Structured_description Provisional_descriptionmsp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. Paper_evidence (5)
Curator_confirmedWBPerson324
Date_last_updated06 May 2005 00:00:00
Concise_descriptionmsp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Molecular_info Corresponding_CDSZK354.5
Corresponding_proteinWP:CE02806
Corresponding_PCR_product smd_C04G2.4
smd_C34F11.6
smd_F32B6.6
smd_F36H12.7
smd_F36H12.7:2
smd_F36H12.8
smd_F58A6.9
smd_K07F5.2
smd_K07F5.3
smd_R05F9.3
smd_R13H9.2
smd_R13H9.2:2
smd_R13H9.4
smd_T13F2.10
smd_T13F2.11
smd_Y4C6A.c
smd_Y59E9_120.c
smd_ZK354.1
smd_ZK354.4
smd_ZK354.11
smd_ZK546.6
sjj_K08F4.8
sjj_ZK546.6
sjj_R13H9.4
sjj_C34F11.6
sjj_Y59E9_120.c
sjj_ZK354.5
sjj_ZK354.1
sjj_R05F9.13
sjj_F26G1.7
sjj_R05F9.8
sjj_T13F2.11
sjj_T13F2.10
sjj_K07F5.1
sjj_K07F5.2
sjj_R13H9.2
sjj_Y4C6A.c
sjj_C04G2.4
sjj_R05F9.5
sjj_ZK354.11
sjj_F58A6.11
sjj_C09B9.6
sjj_F32B6.6
sjj_Y59E9_120.c_1
sjj_R05F9.3
sjj_F58A6.8
sjj_ZK354.4
sjj_F36H12.7
sjj_Y59E9_120.c_2
sjj_K07F5.3
Corresponding_RNAi_reagent (56)
Experimental_info RNAi_resultJA:ZK354.5
WB_RNAi_result (63)
Expr_patternExpr3417
Reference (3)
MethodGene