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Gene: ZK652.9 
| ZK652.9 | Evidence | Paper_evidence | WBPaper00013270 | |||
|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | ZK652 | |||
| Chromosome | III | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | coq | ||||
| Allele | gk379 | |||||
| Strain | VC925 | |||||
| GO_term | GO:0008168 | IEA | Inferred_automatically | |||
| GO:0008757 | IEA | Inferred_automatically | ||||
| GO:0009108 | IEA | Inferred_automatically | ||||
| Contained_in_operon | CEOP3456 | |||||
| Structured_description | Provisional_description | coq-5 encodes a putative ubiquinone biosynthesis methyltransferase, homologous to COQ5 in S. cerevisiae and a family of methyltransferases involved in ubiquinone, menaquinone, biotin and sterol biosynthesis and in phosphatidylethanolamine methylation; COQ-5 is required for ubiquinone biosynthesis and for normally short lifespan; coq-5(RNAi) animals have reduced levels of coenzyme Q8, coenzyme Q9, and superoxide, and have abnormally long lifespans. | Paper_evidence | WBPaper00004424 | ||
| WBPaper00005863 | ||||||
| WBPaper00013580 | ||||||
| Person_evidence | WBPerson567 | |||||
| Curator_confirmed | WBPerson567 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. | ||||||
| Concise_description | coq-5 encodes a putative ubiquinone biosynthesis methyltransferase, homologous to COQ5 in S. cerevisiae and a family of methyltransferases involved in ubiquinone, menaquinone, biotin and sterol biosynthesis and in phosphatidylethanolamine methylation; COQ-5 is required for ubiquinone biosynthesis and for normally short lifespan; coq-5(RNAi) animals have reduced levels of coenzyme Q8, coenzyme Q9, and superoxide, and have abnormally long lifespans. | |||||
| Molecular_info | Corresponding_CDS | ZK652.9 | ||||
| Corresponding_protein | WP:CE29014 | |||||
| KOG | KOG1540 | |||||
| Corresponding_RNAi_reagent (5) | ||||||
| Experimental_info | RNAi_result | Cenix:179-f10 | ||||
| Cenix:305-f7 | ||||||
| TH:305F7 | ||||||
| [pmid12709403]:coq-4 | ||||||
| WB_RNAi_result | TH:305F7 | |||||
| [pmid12709403]:coq-5 | ||||||
| Cenix:305-f7 | ||||||
| Cenix:179-f10 | ||||||
| Reference | WBPaper00005863 | |||||
| WBPaper00006360 | ||||||
| Method | Gene |
